Abstract: Prestressed anchorage has been employed to reinforce northern slope of Haizhou open-pit coal mine in Fuxin City.Therefore,five parameters of prestressed anchorage,namely inter-row spacing of the anchor,prestress,anchorage angle,length of bond part and length of cable,were selected to analyze their sensitivity based on orthogonal experiment design.Sensitivity analysis results suggested that prestress and inter-row spacing of the anchor have the greater sensitivity to the slope stability than that of other three factors which means that prestress and inter-row spacing of the anchor were the main factors determining the stability factor of prestressed anchorage.Thus,an economy and effective control could be made in slope treatment with prestressed anchorage.