Abstract: The transition probability geostatistical software is introduced in this paper.On the basis of borehole data,the hydrogeological structure model in the study area is constructed by using geostatistics condition simulation,and the hydrogeological conceptual model in the study area is constructed by using conceptual model approach.With the aid of hydrogeologic-unit flow package,the integration and the 3-D numerical simulation of groundwater in the Liziyuan wellfield is built and calibrated,and the parameters are defined by lithology.By using this method,water supply of 8×10~4m~3/d in the Liziyuan wellfield is secured,and the safe yield is 26.23×10~4m~3/d.