Abstract: Leakage of phosphorus gypsum storage site especially in karst area has a great effect on groundwater and surface water quality. The methods of connective experiment, geophysical prospecting and drilling are integrated to give a comprehensive study. The main leakage types of the study area are fracture type (Shuangyanjing spring), fracture-channel type (Facaidong karst channel) and channel type (Yacaoba karst channel). Without the impermeable seepage-proofing, leakage to the groundwater will happen through aven doline, dissolved fracture and solution crack. The leakage will transport to S1, S23, S13 and S14 springs. Other springs will not be contaminated for the exitsing of aquitard layer. The leakage exists after the run of the storage site but the pollution of groundwater declined obviously after the run of seepage control system.